Gamboa
"I came for the canal and left having seen more sloths than I've seen in the rest of my life combined."
A former canal-zone town where the jungle presses right up against the waterway, and howler monkeys outnumber people by a wide margin.
Gamboa sits at the exact point where the Chagres River empties into the Panama Canal, and the town itself feels like an afterthought to the engineering around it — a scatter of old Canal Zone houses with wide porches, built for American dredging-division employees decades ago, now half-swallowed by the rainforest that was never fully cleared back. I stayed in one of those houses, and on the first night a two-toed sloth crossed the porch railing at a pace so unhurried it took nearly ten minutes to disappear from view.
The Panama Rainforest Discovery Center just outside town has an aerial observation tower, a repurposed telecommunications structure that climbs above the canopy, and I went up before dawn on the advice of a birder we met at breakfast. It was worth losing the sleep. Toucans moved between the treetops at eye level, a troop of howler monkeys somewhere below made a noise like a jet engine idling, and as the fog burned off, the canal itself became visible in the distance, a container ship gliding past in total silence from that height.

The boat trip up the Chagres is the other essential piece — we hired a panga and puttered upriver past Emberá communities, caimans sunning on the banks, and a family of capybaras that our guide spotted before we’d even registered movement. Gamboa also functions as a jumping-off point for Barro Colorado Island’s research station out on Gatun Lake, though access there is restricted and requires advance permits through the Smithsonian. Even without that, an afternoon on the water here delivers more wildlife sightings per hour than almost anywhere else I’ve traveled.

When to go: The dry season, January through April, gives the clearest skies for the observation tower and the calmest water for river trips, though wildlife sightings are good year-round.